TMS vs Spravato A Comprehensive Guide to Choosing the Right Depression Treatment

When depression does not improve with traditional medications, finding the next step can feel confusing and stressful. Two advanced treatments available at Sonoran Sun Wellness in Arizona are Transcranial Magnetic Stimulation (TMS) therapy and Spravato® nasal spray. Both offer hope for people struggling with treatment-resistant depression, but they work in very different ways. Understanding how each treatment works, who they help most, and what to expect can guide you toward the right choice for your mental health journey.

TMS therapy machine ready for use in a clinical setting

What Is TMS Therapy?

TMS therapy uses magnetic pulses to stimulate specific areas of the brain involved in mood regulation. It is a non-invasive, drug-free treatment that targets brain circuits linked to depression. During a session, a coil placed near the scalp sends magnetic pulses that activate nerve cells in the prefrontal cortex, an area often underactive in depression.

People often choose TMS because it avoids the side effects associated with antidepressant medications. It is typically administered daily over four to six weeks, with each session lasting about 30 to 40 minutes. Many patients notice gradual improvement in mood, energy, and motivation as treatment progresses.

Benefits of TMS

• Non-invasive and does not require anesthesia

• No systemic side effects like weight gain or sexual dysfunction

• Can be used alongside existing medications

• FDA-cleared for treatment-resistant depression

  
  

Who Should Consider TMS?

TMS is a good option for people who:

• Prefer to avoid or reduce medication use

• Have not responded well to multiple antidepressants

• Experience side effects from medications

• Want a treatment with a strong safety record

  
  

What Is Spravato®?

Spravato® is a nasal spray containing esketamine, a form of ketamine approved by the FDA for treatment-resistant depression. It works differently from traditional antidepressants by targeting the brain’s glutamate system, which plays a role in mood and cognition. Spravato can produce rapid relief of depressive symptoms, sometimes within hours or days.

Spravato is used together with an oral antidepressant and administered under medical supervision due to potential side effects like dizziness or dissociation. Treatment usually starts with twice-weekly doses, then tapers to weekly or less frequent maintenance.

Spravato nasal spray device used for depression treatment

Benefits of Spravato

• Rapid symptom relief, especially for severe depression

• Effective for people with suicidal thoughts or acute episodes

• Administered in a controlled medical setting for safety

• Works through a different brain pathway than traditional antidepressants

  
  

Who Should Consider Spravato?

Spravato may be recommended for people who:

• Have severe depression that has not improved with other treatments

• Experience suicidal thoughts or urgent symptoms

• Need faster relief than traditional antidepressants provide

• Can commit to regular visits for supervised treatment

  
  

Comparing TMS and Spravato

Choosing between TMS and Spravato depends on your unique situation. Here are some key factors to consider:

TMS therapy and Spravato® are both advanced treatments for depression, but they work in different ways. TMS is a non-invasive brain stimulation therapy that does not require medication and is typically delivered through daily outpatient sessions, with results developing gradually over several weeks. Side effects are usually mild and limited to temporary scalp discomfort, making it a good option for people who are sensitive to medications. Spravato®, on the other hand, is a medication delivered as a nasal spray and used alongside an oral antidepressant. It is administered in a medical facility under supervision and is known for its rapid effects, often providing relief within hours or days. Spravato may cause side effects such as dizziness or dissociation and is often recommended for individuals with severe depression or suicidal thoughts.

What to Expect During Treatment

At Sonoran Sun Wellness, every patient receives a thorough consultation to discuss symptoms, medical history, and treatment goals. This helps determine which option fits best without pressure.

• TMS sessions involve sitting comfortably while the magnetic coil delivers pulses. Most people resume normal activities immediately after.

• Spravato treatments require monitoring for two hours after dosing to ensure safety. Patients should arrange transportation home.

  
  

Both treatments require commitment to the schedule and follow-up visits to track progress.

Therapy room designed for patient comfort during depression treatments

Making the Right Choice for You

Deciding between TMS and Spravato depends on your preferences and clinical needs. If you want a medication-free approach and can commit to daily sessions, TMS may be ideal. If your depression is severe or includes suicidal thoughts, Spravato’s rapid action could be life-changing.

Both treatments have helped many people regain hope and improve quality of life. The key is working with a trusted provider who listens and supports you through the process.

If you are ready to explore advanced depression treatment options in Arizona, schedule a confidential consultation at Sonoran Sun Wellness. Taking this step can open the door to renewed energy, clearer thinking, and brighter days ahead.